RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
miR-146b-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
luciferase assays
Target
IRAK1;CEACAM1
Pathway
NA
PubMed ID
Title
Therapeutic silencing miR-146b-5p improves cardiac remodeling in a porcine model of myocardial infarction by modulating the wound reparative phenotype
Year
2021
Function
"Overexpression of miR-146b-5p activated fibroblast proliferation, migration, and fibroblast-to-myofibroblast transition, impaired endothelial cell function and stress survival, and disturbed macrophage paracrine signaling."